20 Years of TissueGnostics: Frontiers in Tissue Cytometry, Spatial Phenotyping and Multispectral Imaging



  • Case Study: Analysis of FISH Using Tissue Cytometry
  • COL8A1 promotes tumor in pancreatic ductal adenocarcinoma
  • High-Speed Multispectral Imaging with TissueFAXS CHROMA
  • Characterization of the Spatial Immune Context of Lung Cancer
  • 20 Years of TissueGnostics
  • Webinar: The Effect of Stem Cell Transplantation on Skin Microorganisms

Case Study: Analysis of FISH Using Tissue Cytometry

StrataQuest image analysis software can be used with streamlined solutions, such as the IF Dots App, to ease the evaluation workflow of fluorescence in-situ hybridization (FISH) stainings. Additionally, it can be applied to any analysis of dot-sized objects within the nuclei, which can be combined with AI-based tissue classification, phenotyping, or spatial analysis.

Read more https://tissuegnostics.com/index.php?option=com_content&view=article&layout=edit&id=370

COL8A1 Promotes Tumor in Pancreatic Ductal Adenocarcinoma

Yan et al. investigated several collagen subtypes involved in pancreatic ductal adenocarcinoma desmoplasia. During the study, COL8A1 was suggested as a new marker for predicting poor chemotherapy responsiveness and survival. The TissueFAXS imaging platform and StrataQuest analysis solution were used to image and segment morphological structures.

Read the publication https://pubmed.ncbi.nlm.nih.gov/36375776/

High-Speed Multispectral Imaging with TissueFAXS CHROMA

TissueFAXS CHROMA specializes in multispectral fluorescence whole-slide imaging for up to 7 markers at a time by using an optimized set of SpectraSplit filters. This cost-effective high-speed slide scanner reaches its full potential when combined with TG’s single-cell and contextual image analysis solutions.

Explore here https://tissuegnostics.com/products/multispectral-cytometer/tissuefaxs-chroma

Characterization of the Spatial Immune Context of Lung Cancer

In a recent study, Imamura et al. investigated the role of debrin-expressing tumor infiltration lymphocytes (TIL) in lung cancer. The high-end image analysis solution, StrataQuest, was used for the automatic tissue classification and localization of CD3+/debrin+ cellular phenotypes in the tumor cell nest, as well as in the stroma.

Read publication https://www.mdpi.com/1422-0067/23/22/13723#

20 Years of TissueGnostics

This year TissueGnostics is celebrating its 20-year anniversary. In order to celebrate this achievement, we have put together an article highlighting TG´s most important yearly milestones. These accomplishments wouldn’t have been possible without the support of our wider TG community. For this reason, we have some exciting announcements up-and-coming.

Read more https://tissuegnostics.com/anniversary

The Effect of Stem Cell Transplantation on Skin Microorganisms

Nadine Bayer, PhD, Medical University of Vienna, presents her paper “Disturbances in microbial skin recolonization and cutaneous immune response following allogeneic stem cell transfer”, which was recently published in the high-impact journal Stem Cell Transplantation.

Watch here: https://tissuegnostics.com/webinar-nadine-bayer

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